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Top 15 Largest Pharmaceutical Companies in the World


Here is a list of the top 15 world’s largest pharmaceutical companies in the world based SOLELY on 2023 pharmaceutical drug and vaccine sales revenue.


 Note: 

  • Revenues outside of the pharmaceutical drug and vaccine sales were excluded. E.g. Roche’s diagnostics, J&J’s medtech, MSD’s animal health, Bayer’s crop science and consumer health sales, etc. 
  • In addition, we only consider PLCs, not state-owned enterprises such as Sinopharm. 
  • Data was taken from company annual reports.
  • Revenue in (USD Billions) for 2023 with percentage change from 2022.


1. Pfizer (US) – $58.5 billion -41%

2. Johnson & Johnson (US) – $54.80 billion +4%

3. AbbVie (US) – $54.32 billion -6%

4. Merck & Co. (US) – $53.58 billion +3%

5. Roche (Switzerland) – $48.7 billion -2%

6. AstraZeneca (Sweeden/UK) – $45.8 billion +3.3%

8. Novartis (Switzerland) – $45.44 billion -8%

7. Bristol-Myers Squibb (US) – $45.06 billion -2%

9. Sanofi S.A. (France) – $40.56 billion +0.3%

10. GlaxoSmithKline (UK) – $37.76 billion +3.4%

11. Eli Lilly (US) – $34.12 billion +20%

12. Novo Nordisk (Denmark) – $33.30 billion +31.5%

13. Takeda (Japan) – $30.30 billion +3.5

14. Amgen Inc (US) – $28.20 billion +7%

15. Gilead Sciences (US) – $27.12 billion -0.2%


Highlights:

- Pfizer retains the No.1 position. However, sales dropped from $100.3 billion in 2022 to $58.5 billion in 2023 due to a slowdown in the sales of its COVID-19 vaccine.

- Novo Nordisk’s revenues increased from $25.40 billion in 2022 to $33.30 billion in 2023 mostly due to demand for its diabetes and obesity products Ozempic and Wegovy.

- Eli Lilly saw a 20% jump in revenue from $28.54 billion to $34.12 billion mostly due to demand for to demand for its diabetes and obesity products Mounjaro and Zepbound.

- While Novartis’s total revenue dropped from $50.54 billion to $45.44 billion due to the spin-off of its generics and biosimilar business Sandoz, its core operating revenue grew by 7.7%.


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Rrsource Person: Donagh Fitzgerald

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