Pharmacy Courses

Clinical Pharmacy Questions and Answers



Q1. What is the indication of Neostigmine plus Glycopyrrolate are in the post-op Cardiovascular Surgery order set?

Answer: Reversal of anesthesia and muscle relaxants.


Q2. What is TOF (train-of-four) monitoring?

Answer: It’s a device that delivers a small shock to initiate muscle contraction in 4 spots in the area of the procedure and helps to determine when the effects of neuromuscular blockade agents have begun in a patient.


Q3. What is the maximum dose of Cymbalta (Duloxetine) in a day?

Answer: 120 mg/day


Q4. What is ACR in relation to CKD (Chronic Kidney Disease)?

Answer: Albumin creatinine ratio


Q5. What is the meaning of ACR value?

Answer:

1. ACR of 3 or higher = indication of ACEi/ARB for patients with comorbid DM

2. ACR of 30 or higher = indication of ACEi/ARB for patients with comorbid HTN

3. ACR of 70 or higher = indication of ACEi/ARB irregardless of comorbidities


Q6. Which drugs are Mineralocorticoid (Aldosterone) Receptor Antagonists?

Answer:

  • Aldactone
  • Eplerenone
  • Spironolactone


Q7. What is the duration of action (hours) for Bumetanide and Furosemide?

Answer: Bumetanide 4 to 6 hours and Furosemide 6 to 8 hours.


Q8. What is White Coat Effect or White Coat Syndrome?

Answer: Higher blood pressure reading while checking.


Q9. It says - “If you have protein C or protein S deficiency, you must never receive warfarin without first receiving another anticoagulant at the same time.” Why?

Answer: Because warfarin inhibits protein C and S (anticoagulant factors) first so it can cause clots, especially in patients who already have protein C and S deficiencies. So, you’ll need another anticoagulant to give warfarin time to inhibit clotting factors II, VII, IX, and X.


Q10. How is Ejection Fraction (EF) related with Coumadin (Warfarin) dosing?

Answer: A low ejection fraction may indicate that a patient may need a lower dose of warfarin.


Q11. Which drugs are used for cardiac stress test?

Answer: Dobutamine, Dipyridimole etc.


Q12. What would you consider the maximum duration of treatment for Vigamox (Moxifloxacin) eye drop?

Answer: 7 days for bacterial conjunctivitis.


Q13. Which Gene Testings May Be Considered for Warfarin?

Answer: VKORC1, CYP4F2 and CYP2C9.


Q14. A physician ordered Vitamin K 10 mg oral once daily for 5 days for a critical patient in ICU. What would be your guess for the indication?

Answer: Acutely decompensated cirrhosis.


Q15. For Withdrawal Seizures from Alcohol Withdrawal Syndromes which meds are recommended to use and which anticonvulsants are not recommended to use?

Answer:

1. Benzodiazepines, Phenobarbital and Propofol are recommended.

2. Carbamazepine, Valproate and Levetiracetam are not recommended.


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