Pharmacy Courses

Edging and Chipping | Tablet Problems and Remedies



Edging

Edging is a tablet defect in which sharp edges appear on the final compressed tablet. This type of tablet defect also known as collaring of tablet.


Causes

  • High moisture content in granules
  • Waxy or elastic nature of API or excipients in formulation
  • Higher compression pressure
  • Poor punch design or improper selection of punch


Remedies

  • Proper milling and drying
  • Compression pressure adjustment
  • Proper design of punch


Chipping

Chipping is a tablet defect in which breaking of tablet edges during compression process or subsequent handling and coating.


Causes

  • Insufficient binder
  • Too dry granules
  • Improper punch setting
  • Rough surface of punches and dies


Remedies

  • Sufficient binder
  • Moisten the granules
  • Proper punch setting
  • Right choice of tooling (punches and dies)



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